There hasn’t been much research yet to definitively say that African Mango extracts can help with weight loss. The scientific studies that have been conducted suffer from some issues. Many are very small studies. Some laboratory studies involve the extract in cultures or with animal subjects, which have very limited generalizability to humans. Some have methodological flaws, and there are a couple of studies that may have conflicts of interest by being sponsored by supplement manufacturers. As a result, any claims should be taken with a grain of salt.
African Mango Laboratory Tests
But there are some promising possibilities. One in vitro study suggested that African mango seed extract could reduce fat cell proliferation and triglyceride uptake. Since the study observed this effect in laboratory cultures, it’s unknown if these effects would also be seen in the human body.
Studies in rats have yielded mixed results. A laboratory study using rats found that high levels of consumption of African mango seeds caused both an increase in high-density lipoprotein cholesterol (also known as “good cholesterol”) and a rise in triglycerides. Another study administered extracts of African mango bark and leaves to diabetic rats. While some rats showed lower blood sugar levels after receiving aqueous extracts of mango leaves, others gained weight. Questions arose concerning the potential toxicity of the mango extracts in this study.
Digging into Clinical Data on Dika
A double-blind randomized study of forty human subjects found that those who took African mango experienced a significant decrease in body weight. This experimental group also showed decreases in low-density lipoprotein cholesterol (also known as “bad cholesterol”), triglycerides, and total cholesterol levels. Meanwhile, the subjects’ levels of high-density lipoprotein cholesterol increased.
Similar effects were also found in study of a compound that combined Veldt grape and African mango. This double-blind, placebo-controlled, randomized study tracked the effects of the grape-mango combination on obese and overweight human subjects. Subjects who received the compound showed significant improvements in body weight, low-density lipoprotein cholesterol, blood glucose levels, body fat, waist measurement, and total plasma cholesterol as compared to the control group. However, given that this study used a combination of weight-loss ingredients, it’s difficult to tease out the actual effects of African mango extract independent of the Veldt grape.
A randomized, double-blind, placebo-controlled study following the progress of overweight subjects found some weight loss among people who took African mango. However, the weight reduction effects were not measurable until several weeks into the study. Additional testing showed some improvements in lipid measurements for the experimental group, compared to the control group.
Another double blind, randomized, placebo-controlled clinical trial included one hundred and two subjects without major health problems. In this study, subjects were given a proprietary extract of African mango seed. Some beneficial effects on metabolic parameters and body weight were observed in the experimental group.
Mango in Review
A systematic literature review in a peer-reviewed journal examined the existing research on several medicinal plants with purported anti-obesity properties. This exhaustive review noted that while African mango showed some beneficial weight loss effects in some studies, it was not shown to be as effective as many of the other plants included in the review.
While initial research may give us some promising leads, the bottom line is that additional research is needed to conclusively determine the effectiveness of African mango for weight loss.
Source: African Mango – Leaf Mother